|
|
|
|
|
|
||
|
|
||
|
|
Have you ever taken the drug Vioxx or celebrex? In September 2004 the drug manufacturer Merck decided to recall the product after long term data suggested a serious potential side effect.
This drug and others like it such as as 'Celebrex', 'Bextra' and 'Arcoxia' are part of a family of drugs known as "COX2 drugs" or "COX2 inhibitors"
They have been developed with, ironically, patient safety in mind.They are typically used in treatment of arthritis, though high dose vioxx was promoted for short term relief of acute muscular/skeletal pains.They were anti-inflammatory drugs.
The serious side effects were in connection with the heart suggesting risk of heart disease or heart attack.In medical circles it was referred to as "..adverse cardiovascular effects."
There are other drugs used to treat inflammation that have been around for many years.YOu may have heard of products such as Advil or Nurofen which contain the ingredient Ibuprofen.Other older anti-inflammatory drugs include such brands as Voltarol or Naprosyn.
What's the difference between these older drugs and the recent treatments know as "COX2 drugs"?
The newer drugs such as Arcoxia,Celebrex and Vioxx were designed to be much more specific in their mode action than old drugs like Ibuprofen.The idea was to limit the associated problems in long term treatment.
When we get older we all seem to get more sensitive to side effects of drugs.Often this is complicated even more by the fact that we may suffer from more than one problem or disease at the same time.
At this point we take more medication in the last five to ten years of our lives than in all the other years put together! Is it any wonder we might feel under the weather, a little off colour even?
You could have asthma and high blood pressure. Anxiety and lack of sleep every night. Panic attacks and depression.
If you take an anti-inflammatory drug for a given length of time, your doctor/physician will no doubt tell you about one major problem.
Ulceration of the stomach or intestines.....
It was hoped that the newer COX2 drugs would not cause this problem at all.Therefore it would avoid the risk of someone suffering internal bleeding which could become fatal.
The older you become the greater the risk of this occuring. It could be a slow blood loss or a sudden episode of an ulcer bleeding more profusely.
So when people got the signs of ulcers, they got treatment for an ulcer. Some would stop taking medication and others would take a maintenance dose to prevent ulcers coming back while continuing to take the old ibuprofen drugs for their arthritis.
It was hoped drugs like vioxx would stop this, but ulceration still remains a possibility. Doctors routinely consider offering anti ulcer drugs to reduce the probability of this happening.
So what is the all the recent fuss about ? Where did it all suddenly seem to unravel after all that hope and expectation ? A new long term study seemed to indicate some degree of risk to the heart some 18 months or so after starting treatment.
So if you took vioxx for a week or a couple of months, this potential problem did not appear.It has only been spotted after taking the medication for a longer period such as 18 months.
What can you do? Are there ways to reduce risks? This is something you need advice on as only your doctor will have your medical history.There is much to consider and such a problem can in some circumstances be minimised.
Of course if you smoke you increase the risk of stomach or intestinal ulceration if you also take anti-inflammatory drugs such as Ibuprofen.Why not quit instead?
If you take other medication for depression or anxiety then these drugs can increase the risk of bleeding with any anti-inflammatory drug being taken at the same time.
For more related information visit
http://www.AnxietyAttacksCure.com - a site that offers advice for avoiding, coping with anxiety and panic attacks. Get professional knowledge on dealing with symptoms, drug side effects and improving your life!



As any dialysis patient will tell you, keeping your fluid gain between dialysis sessions in check is not only important to your long term health, it is a major factor in your immediate... Read More
Leading online pharmacy companies are providing consumer with a secure, safe, convenient, and discreet way to acquire prescriptions.People in need of prescriptions are turning to the internet for an alternative to the corner... Read More
I recently had a reader send me this comment:"As a full-time dad I have to deal with just about every minor illness my two children pickup, everything from a bump on the head... Read More
Consider this:Already since 1972, over 60 million people in the USA alone have successfully quit smoking!At one stage over 60% of the adult population was addicted to this drug. Today it is 28%... Read More
Although you make a patient feel better, there isn't usually anything tangible to be a reminder of your service. When it comes time for the patient to pay their bills, yours is often... Read More
The FDA (Food and Drug Administration) is responsible for overseeing the testing, manufacturing, and distribution of prescription drugs in the United States.Drug companies in the United States operate in a free market and... Read More
Every year about this time doctors around the world are recommending that people go in and get their annual flu shot. What most people don't know or understand is just how dangerous this... Read More
Tumescent liposuction is done using a local aesthetic. A large volume of saline solution containing the aesthetic and a drug called "Epinephrine" is injected directly into the areas where there are excessive fatty... Read More
When an unconscious patient arrives in the ED, every hospital agrees that timely next of kin notification is vital. Not only is it important to have a family member present to comfort the... Read More
Bextra, also known as valdecoxib, is a prescribed medication used to alleviate the problems associated with arthritis and other inflammation-related conditions. The drug helps reduce the pain of swelling and fever without causing... Read More
Perhaps one of the most insidious dangers in modern technology is medical testing. Although it would be nice to be able to visit our doctor and get all hooked up with electrodes, inflatable... Read More
Molluscum contagiosum treatment is certainly possible with the correct treatment information.Many people are told that molluscum contagiosum must be left to run its course (even by dermatologists). This can take years.I have written... Read More
The U.S. government's annual bill for healthcare spending ? $3,925 per person ? significantly exceeds that of all other nations. Despite this, our current health care system is increasingly failing both patients and... Read More
Marketing Authorisation: Medicinal Products The case of R (on the application of Merck Sharp and Dohme Ltd) v Licensing Authority [2005], concerned the application for marketing authorisation for a generic product which was... Read More
Hernia repair is one of the most commonly performed surgical procedures worldwide. In fact, there are over 600,000 hernia repair surgeries performed each year in the U.S. alone. A hernia is a weakness... Read More
I remember a friend in college who would blush, sweat, and tremble when required by a teacher to speak in class. A few weeks before the presentation, he'd be anxious, agitated, and couldn't... Read More
We have all talked a lot about the problems in our educational system, about latchkey kids, about teacher turnover (50 percent of teachers quitted within the first five years on the job), psychologists... Read More
Don't treat your migraines, prevent them. A life without migraines is obtainable, I know. I was a migraine sufferer for 12 years and have been treating... preventing them for my patients for 15... Read More
Satins are pharmacuetical drugs that work by restricting the enzyme HMG CoA reductase. This is an enzyme which regulates how fast a rate cholesterol is produced in the body. By slowing down production... Read More
How many of us have taken aspirin or a similar popular product found at the drug store when we had some type of discomfort? Of course, many of us have and why shouldn't... Read More
Cold-Eeze is a homeopathic solution to the common cold. It is a zinc-based solution that can be taken as a tablet or a nasal spray. Limited studies have found that the nasal spray... Read More
Chinese Medicine, over 2000 years old, is an ancient form of medicine. Consisting of acupuncture, moxibustion (moxibustion - using material made up of "moxa-wool," in a form of a cone or stick; moxibustion... Read More
While there are numerous options for people to lower cholesterol naturally, thousands and thousands of people are taking prescription medication to lower cholesterol ? risking some very dangerous side effects.These side effects can... Read More
The recent removal of several high profile and popular prescription pain medications of the same pharmaceutical family, nonsteroidal anti-inflammatories, from the buyer's market has left many people searching for a safer alternative for... Read More
Pill Proof LLC introduces the first, easy to use medication compliance kit for consumers and medical professionals. Owner, Jane Langdon, has a sister in law with Parkinson's Disease. While visiting her sister in... Read More
Electronic Medical RecordAn Electronic Medical Record is a secured electronic file of patient history, medical transcription notes, billing information, and all other information necessary to have a complete patient profile. It is true... Read More
Pain and Stress. They seem almost to go hand in hand - not only in their negative connotation, but also in their biological causes and triggers. Back pain and muscle pain is typically... Read More
When you (or loved ones) are taking prescription or over the counter medications...there is a lot you should be worried about, and a lot that your pharmacist may not be telling you.Most people... Read More
This report will give you 22 important tips to make sure that you're getting the very best out of your arthritis treatment program.1. Make absolutely sure that the nurse or doctor knows what... Read More
According to the Los Angeles Times, the California Association of Physicians and Surgeons, and even the Center for Diseases Control's own admission, well over 100,000 people in this country die each year from... Read More
RA is a condition that forces half of patients to become disabled from the work force within five to ten years? and reduces life expectancy by as much as 18 years. RA affects... Read More
Since early 2004, it has become more apparent every day that the online pharmacy industry is being destroyed. Who is doing such damage to bring the industry crashing down, you ask? So far,... Read More
Ephedra is a naturally occuring herbal dietary supplement that has been marketed as a weight loss drug. The principal active ingredient is an amphetamine-like compound. Because it has been marketed as an herbal... Read More
I had a call the other day from a potential client in a serious situation. He was young and had been diagnosed with CAD (Coronary Artery Disease), suffering from extremely high blood pressure... Read More
Q. Why is there so may uninsured people in America?A. There are over 44 million uninsured people in this country and over 75 million underinsured because of three main factors:1. Insurance rates continue... Read More
Sjogren's syndrome is an autoimmune disorder ? a disorder in which your body attacks its own tissues because it thinks they are foreign. It prevents your body's exocrine (moisture-producing) gland from producing enough... Read More
New antidepressant development, until fairly recently, was at best a random, and at worst a problematic and frustrating, process. Often, medications that were developed for one thing were discovered quite accidentally to have... Read More
Remember the last time you stubbed your toe? OUCH! It's painful. But a stubbed toe usually doesn't send us running to the medicine cabinet, since we know that the pain will pass within... Read More
As Pres. Bush was touring the Midwest, shortly before he was re-elected as President, and even after, he spoke of medical reform centering on liability costs. He called it "defensive medicine." Searching for... Read More
Can you always trust your dentists' recommendations? Think for yourself - in the last 30 years the health of our teeth has improved dramatically. We drink fluoridated water, which almost eliminated decay in... Read More
It was around 1986, when my son Lewis was diagnosed of having ADHD. I like using the term "accused" of having ADHD. I really disagree with anyone who goes this route to get... Read More
Hypnotherapy is one of the best known and most widely used treatments for IBS, and can offer sufferers a drug-free solution to their symptoms of diarrhea, constipation, stomach pain and bloating.There are now... Read More
Would you buy groceries without knowing their prices? I suspect not. You probably compare the costs of different boxes of cereal in order to get the best deal. But when it comes to... Read More
A generic drug can be defined as an identical, or bioequivalent to a brand name drug in its dosage form, safety, strength, route of administration, quality, performance characteristics and intended use. Although generic... Read More
When a health care professional uses lab coats it conveys several different messages. First, lab coats give an appearance of professionalism. It's very important in the health care setting to be professional and... Read More
Many people today realize the importance of keeping their blood pressure under control. Blood pressure monitors are now available for home use.It's a piece of medical equipment that can provide both you and... Read More
At the urging of the Food and Drug Administration, the drugs Vioxx and Bextra have both been voluntarily withdrawn from the market by their manufacturers. Studies show that these drugs, part of a... Read More
Irritable bowel syndrome sufferers often find that they have to deal with two sets of symptoms. The physical symptoms of diarrhea, constipation and pain form the main part of IBS, but sufferers may... Read More
Checklist of Treatments for Alzheimer's DiseasePart 2 of 82. Vitamin E combined with Vitamin C. Vitamin E is a powerful antioxidant that should be taken by nearly all people, not just those afflicted... Read More
Any dialysis patient who has had a brush with high potassium will know only too well how dangerous this can be. We are forever being told to watch our potassium intake, so I... Read More
Finding the right treatment for any person suffering with a drug abuse problem can be a difficult task - where do you start, how do you know what to look for, how do... Read More
A wee bit of fluoride makes teeth and dentists happy, we're told. Dr. Happy Tooth's smiley face turns into a frown when his favorite decay buster is busted as a killer. Anything in... Read More
When was the last time you enjoyed a good night's sleep? I'm talking about feeling tired, heavy, and relaxed - the times when you might say "wow! I love air conditioning" and fall... Read More
Electronic Medical RecordAn Electronic Medical Record is a secured electronic file of patient history, medical transcription notes, billing information, and all other information necessary to have a complete patient profile. It is true... Read More
I remember a friend in college who would blush, sweat, and tremble when required by a teacher to speak in class. A few weeks before the presentation, he'd be anxious, agitated, and couldn't... Read More
One of the most prevalent and difficult health conditions to treat in the physical medicine is low back pain. The difficulty in treating low back pain comes from the fact that there are... Read More
Many natural changes in fingers and toenails come with age. Fine ridges, for example, may start developing from the cuticle of the nail tip. This and other similar changes are common, but they... Read More
Warning: This article is for information only and can not be used to supplement your doctor's advice. You should contact your doctor for nail fungus treatment.Treatment Of Toe Nail FungusMedical Care:Several years ago... Read More
| GOOGLE AD |
Medicine Medicine |